Earlier this month it was announced that Liberty Media, the American entertainment company which also owns F1, acquired a 86% stake in Dorna Sports, valuing the MotoGP, WorldSBK and MotoE promoter at €4.2 billion.
It revived the idea of the two championships experimenting with a joint weekend, which according to Dorna sporting director Carlos Ezpeleta was "not discarded" but not actively worked on either.
COTA chairman Epstein, whose circuit hosted last week's eventful Grand Prix of the Americas and welcomes F1 in October, believes a double-header with both series would be possible but faces several stumbling blocks.
"I think there are complications beyond the obvious," Epstein told selected media, including Autosport.
"The first ones that come to mind are just the physical ones, but from a sponsor activation standpoint they both bring different sponsors, different activations and manufacturers, that we would be bulging at the seams.
"And also, you'd have to do a lot of changeover of track signage. The media centre would bulge a little bit at the seams. It's possible, I don't know that it's probable."
But amid struggles to expand MotoGP's fanbase in North America, Epstein welcomed Liberty's arrival with open arms, saying his circuit will be "one of the biggest beneficiaries".
Source: Autosport