The six-time premier class champion departs the Japanese manufacturer at the end of this weekend, joining Gresini Ducati for 2024 alongside brother Alex.
The move, confirmed in October, ends Marquez's 11-year stay with the team, where he won all his titles with 59 race wins and 101 podiums.
The Spanish rider has endured a difficult four seasons after a season-ending injury at the 2020 Spanish GP, returning in 2021 before suffering a second bout of diplopia later that year.
Marquez missed a further grand prix last year because of the same issue, and has had ongoing struggles with Honda's RC213V.
Though he admits he "would like" a fairytale farewell from the team, Marquez accepts he "needs to be realistic" heading into the weekend.
Asked what was possible to say goodbye in the best possible way, he said: "I don't know, it's a circuit that I like, it's a layout that I like, but the last races have been struggling a bit.
"So let's see on Friday where we are, let's see during the weekend where we are. Of course I cannot try any crazy things, of course I would like, but in the end we need to be realistic and I will try to do my best as I did in the last races.
"Let's see, but first goal is try to enjoy the weekend with all my people."
Source: Autosport