At a circuit that Hamilton has always enjoyed, he qualified fifth in the shootout but fell away to a distant seventh in the sprint itself, losing places to Charles Leclerc and Yuki Tsunoda.
In just 24 laps he dropped 34.7 seconds behind winner Max Verstappen, having chased the Dutchman home in the US GP before his disqualification, and also put in a charging drive to second in Mexico.
"The last couple of races we've been excited that we're progressing, and it's been really positive to see," said Hamilton.
"And you come to another track and then you have the worst deg that you've had for ages. So it's like you just don't know what to expect with this one.
"But only a couple more races with this car and it's gone, and I'll be happy! This year, you're just counting down the days, trying to enjoy every day as you can."
Hamilton said that he struggled with the balance of the car from the early stages.
Source: Autosport