The FIM announced on Wednesday that next year's calendar will take in 22 rounds beginning in Qatar on 10 March and finishing in Valencia on 17 November.
The new schedule features the return of the Aragon Grand Prix, which has been absent for 2023, as well as the second attempt at staging the Kazakhstan GP after it was cancelled this year.
With the new-for-2023 format featuring sprints, a number of riders have raised concerns about the added stress of a grand prix weekend.
"From my point of view, I think it's the limit," 2021 champion Quartararo said on Thursday at the Japanese GP.
"It's clearly the limit. But, the problem is it's not only 22 races – it's 22 sprints [also].
"Mentally, physically the weekend is totally different. You can see how many injuries there are this year. But already from Friday morning you have to be on the limit.
"Last year, more or less, you could start FP1 much easier, you make a time attack in FP2 and then in FP3 is where you really start to push yourself to the limit.
"With this schedule that we have, you are on the limit all the time.
"And this, for me, is the problem. Of course, more than 22 races I think is not possible because physically it's totally different than Formula 1. This is super important."
Eight-time world champion Marc Marquez echoed Quartararo's comments, while also noting that the increase in injuries in 2023 is directly linked to the amount of race starts there are now.
Source: Autosport