The Dutchman saw off an early assault from the two McLarens at the start of the race, and lived up to Lando Norris' pre-race prediction that the Woking team would have little answer to the Dutchman if he led beyond Turn 2.
Verstappen crossed the line 19.3s clear of Norris at the line, having been considerably out of reach across the 53-lap race at Suzuka beyond the opening laps.
The only moments of close action that the championship leader faced was in his defence of the lead into the first corner, as he pulled across to the inside of the turn to ward off any threat from fellow front-row start Oscar Piastri.
Norris then placed his car on the outside, but could not get enough purchase into the second corner to come up for air with the lead - but displaced Piastri nonetheless in the process.
The Briton then attempted to challenge Verstappen on a subsequent restart after a lap 1 safety car was produced to clear debris resulting from a clash between Valtteri Bottas and Alex Albon when the Finn was guided into the Williams driver's side by Esteban Ocon.
But Verstappen gunned the throttle on the exit of the Casio Triangle chicane, and proceeded to begin his usual efforts to build a break over the rest of the field.
Source: Autosport