Palou scored his third win of the season at Road America on Sunday, extending his lead to 74 points over his team-mate Marcus Ericsson.
In securing his team's 250th race victory, the 2021 champion is now 81 points clear of best non-Ganassi driver Newgarden.
But the Indianapolis 500 winner, who finished second on Sunday, shrugged off the deficit as the series approaches its halfway point at Mid-Ohio next month.
“Probably win by 200 points if you won nine races straight,” he said. “Yeah, I mean, it's pretty wide open still.”
Newgarden pointed to Palou’s consistent points scoring, even bouncing back to finish fourth in the Indy 500 after a pitroad collision with Rinus VeeKay put Palou in the wall and broke his front wing – which dropped him to last place for a time.
“It's kind of out of our control,” he admitted of Palou’s metronomic scoring.
“They've had a good run up to this point, right? They've not had a bad race. I think that's to be expected.
“We had an engine pop on us in the very first round. Everybody has a different story.
“If you look at their story, they've not had one bad race yet. When you have eight races in a row without a bad one, this is what happens points-wise.
Source: Autosport